Simple Connectome Inference from Partial Correlation Statistics in Calcium Imaging

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Antonio Sutera, Arnaud Joly, Vincent Francois-Lavet, Aaron Qiu, Gilles Louppe, Damien Ernst, Pierre Geurts ;
Proceedings of the Neural Connectomics Workshop at ECML 2014, PMLR 46:23-35, 2015.

Abstract

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to detect neural peak activities. Second, inferring the degree of association between neurons from partial correlation statistics. This paper summarises the methodology that led us to win the Connectomics Challenge, proposes a simplified version of our method, and finally compares our results with respect to other inference methods.

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