Towards data-driven stroke rehabilitation via wearable sensors and deep learning

Aakash Kaku, Avinash Parnandi, Anita Venkatesan, Natasha Pandit, Heidi Schambra, Carlos Fernandez-Granda
Proceedings of the 5th Machine Learning for Healthcare Conference, PMLR 126:143-171, 2020.

Abstract

Recovery after stroke is often incomplete, but rehabilitation training may potentiate recovery by engaging endogenous neuroplasticity. In preclinical models of stroke, high doses of rehabilitation training are required to restore functional movement to the affected limbs of animals. In humans, however, the necessary dose of training to potentiate recovery is not known. This ignorance stems from the lack of objective, pragmatic approaches for measuring training doses in rehabilitation activities. Here, to develop a measurement approach, we took the critical first step of automatically identifying functional primitives, the basic building block of activities. Forty-eight individuals with chronic stroke performed a variety of rehabilitation activities while wearing inertial measurement units (IMUs) to capture upper body motion. Primitives were identified by human labelers, who labeled and segmented the associated IMU data. We performed automatic classification of these primitives using machine learning. We designed a convolutional neural network model that outperformed existing methods. The model includes an initial module to compute separate embeddings of different physical quantities in the sensor data. In addition, it replaces batch normalization (which performs normalization based on statistics computed from the training data) with instance normalization (which uses statistics computed from the test data). This increases robustness to possible distributional shifts when applying the method to new patients. With this approach, we attained an average classification accuracy of 70%. Thus, using a combination of IMU-based motion capture and deep learning, we were able to identify primitives automatically. This approach builds towards objectively-measured rehabilitation training, enabling the identification and counting of functional primitives that accrues to a training dose.

Cite this Paper

BibTeX
@InProceedings{pmlr-v126-kaku20a, title = {Towards data-driven stroke rehabilitation via wearable sensors and deep learning}, author = {Kaku, Aakash and Parnandi, Avinash and Venkatesan, Anita and Pandit, Natasha and Schambra, Heidi and Fernandez-Granda, Carlos}, booktitle = {Proceedings of the 5th Machine Learning for Healthcare Conference}, pages = {143--171}, year = {2020}, editor = {Doshi-Velez, Finale and Fackler, Jim and Jung, Ken and Kale, David and Ranganath, Rajesh and Wallace, Byron and Wiens, Jenna}, volume = {126}, series = {Proceedings of Machine Learning Research}, month = {07--08 Aug}, publisher = {PMLR}, pdf = {http://proceedings.mlr.press/v126/kaku20a/kaku20a.pdf}, url = {https://proceedings.mlr.press/v126/kaku20a.html}, abstract = {Recovery after stroke is often incomplete, but rehabilitation training may potentiate recovery by engaging endogenous neuroplasticity. In preclinical models of stroke, high doses of rehabilitation training are required to restore functional movement to the affected limbs of animals. In humans, however, the necessary dose of training to potentiate recovery is not known. This ignorance stems from the lack of objective, pragmatic approaches for measuring training doses in rehabilitation activities. Here, to develop a measurement approach, we took the critical first step of automatically identifying functional primitives, the basic building block of activities. Forty-eight individuals with chronic stroke performed a variety of rehabilitation activities while wearing inertial measurement units (IMUs) to capture upper body motion. Primitives were identified by human labelers, who labeled and segmented the associated IMU data. We performed automatic classification of these primitives using machine learning. We designed a convolutional neural network model that outperformed existing methods. The model includes an initial module to compute separate embeddings of different physical quantities in the sensor data. In addition, it replaces batch normalization (which performs normalization based on statistics computed from the training data) with instance normalization (which uses statistics computed from the test data). This increases robustness to possible distributional shifts when applying the method to new patients. With this approach, we attained an average classification accuracy of 70%. Thus, using a combination of IMU-based motion capture and deep learning, we were able to identify primitives automatically. This approach builds towards objectively-measured rehabilitation training, enabling the identification and counting of functional primitives that accrues to a training dose.} }
Endnote
%0 Conference Paper %T Towards data-driven stroke rehabilitation via wearable sensors and deep learning %A Aakash Kaku %A Avinash Parnandi %A Anita Venkatesan %A Natasha Pandit %A Heidi Schambra %A Carlos Fernandez-Granda %B Proceedings of the 5th Machine Learning for Healthcare Conference %C Proceedings of Machine Learning Research %D 2020 %E Finale Doshi-Velez %E Jim Fackler %E Ken Jung %E David Kale %E Rajesh Ranganath %E Byron Wallace %E Jenna Wiens %F pmlr-v126-kaku20a %I PMLR %P 143--171 %U https://proceedings.mlr.press/v126/kaku20a.html %V 126 %X Recovery after stroke is often incomplete, but rehabilitation training may potentiate recovery by engaging endogenous neuroplasticity. In preclinical models of stroke, high doses of rehabilitation training are required to restore functional movement to the affected limbs of animals. In humans, however, the necessary dose of training to potentiate recovery is not known. This ignorance stems from the lack of objective, pragmatic approaches for measuring training doses in rehabilitation activities. Here, to develop a measurement approach, we took the critical first step of automatically identifying functional primitives, the basic building block of activities. Forty-eight individuals with chronic stroke performed a variety of rehabilitation activities while wearing inertial measurement units (IMUs) to capture upper body motion. Primitives were identified by human labelers, who labeled and segmented the associated IMU data. We performed automatic classification of these primitives using machine learning. We designed a convolutional neural network model that outperformed existing methods. The model includes an initial module to compute separate embeddings of different physical quantities in the sensor data. In addition, it replaces batch normalization (which performs normalization based on statistics computed from the training data) with instance normalization (which uses statistics computed from the test data). This increases robustness to possible distributional shifts when applying the method to new patients. With this approach, we attained an average classification accuracy of 70%. Thus, using a combination of IMU-based motion capture and deep learning, we were able to identify primitives automatically. This approach builds towards objectively-measured rehabilitation training, enabling the identification and counting of functional primitives that accrues to a training dose.
APA
Kaku, A., Parnandi, A., Venkatesan, A., Pandit, N., Schambra, H. & Fernandez-Granda, C.. (2020). Towards data-driven stroke rehabilitation via wearable sensors and deep learning. Proceedings of the 5th Machine Learning for Healthcare Conference, in Proceedings of Machine Learning Research 126:143-171 Available from https://proceedings.mlr.press/v126/kaku20a.html.

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