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Integrating AI-Driven Triage into Digital Pharmacy Systems for Rational Antibiotic Use in Low-Resource Settings
Proceedings of The Second AAAI Bridge Program on AI for Medicine and Healthcare, PMLR 317:102-109, 2026.
Abstract
Antimicrobial resistance (AMR) is becoming a bigger threat to global health, especially in low- and middle-income countries (LMICs), where antibiotics are often given out without a prescription. This study presents a hybrid Artificial Intelligence (AI) framework to improve rational antibiotic utilization by integrating pharmacies, telemedicine practitioners, and policymakers through an integrated digital infrastructure. The digital intervention system was implemented in 28 community pharmacies and showed significant improvements in how people used antibiotics. Specifically, the percentage of people who self-medicated with antibiotics dropped from 4.05% to 0.86%, and the percentage of people who bought antibiotics with a prescription jumped from 27.6% to 43.5%. We propose an AI framework that combines a machine learning (ML)-based and a large language model (LLM)-based symptom checker for intelligent triage and clinical decision support. These models will enable efficient analysis of both structured and narrative symptom data, which will help pharmacists provide advice and doctors refer patients right away. The suggested model demonstrates a scalable, data-driven, and human-in-the-loop approach to antibiotic stewardship, with the potential to support future AMR mitigation and healthcare accessibility in LMICs settings.