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High-Resolution Micro-Patching: A Zero-Leakage Microaneurysm Baseline
Proceedings of IndabaX Nigeria 2026: Building Scalable AI That Works: From Research to Deployment in Resource-Constrained Environments, PMLR 319:217-231, 2026.
Abstract
We propose a patient-isolated microaneurysm segmentation scheme that maintains lesion geometry via high-resolution micro-patching. Rather than scaling full fundus images, the technique takes native-resolution spatial crops, preserving small lesion structure that resizing erases. A hybrid encoder-decoder with spatial and channel attention mechanisms suppresses background and emphasises rare vascular abnormalities. Zero-leakage training is applied, and cross-domain performance is evaluated on datasets with varying demographics and resolutions. Results show that native resolution is more robust to distribution shift and consistent in diagnostic sensitivity across unseen domains.