Exploring the Mind: Integrating Questionnaires and fMRI

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Esther Salazar, Ryan Bogdan, Adam Gorka, Ahmad Hariri, Lawrence Carin ;
Proceedings of the 30th International Conference on Machine Learning, PMLR 28(2):262-270, 2013.

Abstract

A new model is developed for joint analysis of ordered, categorical, real and count data. The ordered and categorical data are answers to questionnaires, the (word) count data correspond to the text questions from the questionnaires, and the real data correspond to fMRI responses for each subject. The Bayesian model employs the von Mises distribution in a novel manner to infer sparse graphical models jointly across people, questions, fMRI stimuli and brain region, with this integrated within a new matrix factorization based on latent binary features. The model is compared with simpler alternatives on two real datasets. We also demonstrate the ability to predict the response of the brain to visual stimuli (as measured by fMRI), based on knowledge of how the associated person answered classical questionnaires.

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